
When High Blood Pressure Doesn't Respond to Treatment
For many with high blood pressure, lifestyle changes and medication can keep hypertension controlled. However, others suffer from resistant hypertension, in which blood pressure remains high despite various medication trials.
Today, there is a new option available for blood pressure control called renal artery denervation (RDN), a minimally invasive option for those who need further control than medication alone. Dr. Manish Taneja at our specialized vascular clinic in Singapore can help with this high blood pressure treatment.

Common Questions About Renal Artery Denervation for High Blood Pressure
What is renal artery denervation?
Renal artery denervation (RDN) is a minimally invasive procedure that uses catheter-based technology to reduce overactivity of nerves surrounding the renal arteries. These nerves play a role in regulating blood pressure, and modifying their activity may help lower blood pressure in selected patients.
Who may benefit from renal denervation?
Renal denervation may be considered for some patients with uncontrolled or difficult-to-manage hypertension despite appropriate medical treatment and lifestyle changes. Suitability depends on factors including blood pressure control, medications, kidney health and overall cardiovascular risk.
Is renal denervation an alternative to blood pressure medication?
Renal denervation is not a replacement for medication in every patient. Some patients may continue taking blood pressure medications after the procedure. A specialist assessment helps determine whether renal denervation may be a suitable addition to existing treatment.
How is renal denervation performed?
Renal denervation is performed using a catheter inserted through a blood vessel, usually through a small access point. Image guidance allows the specialist to treat the nerves around the renal arteries without open surgery.
What happens after renal artery denervation?
After the procedure, patients require ongoing blood pressure monitoring and follow-up care. Your specialist will assess your response to treatment and continue managing other factors that affect cardiovascular health.
Understanding the Renal Sympathetic Nervous System
The renal sympathetic nervous system causes the heart to beat faster when you are under stress or facing some type of danger.
The renal sympathetic nervous system also causes the kidneys to retain sodium and water while releasing renin, the enzyme that controls blood pressure. This increases the volume of blood released while constricting the blood vessels, leading to an elevation in blood pressure.
What is Renal Artery Denervation?
RDN is a minimally invasive catheter-based procedure that is typically performed as an outpatient within a hospital, although some patients may be monitored overnight.
The procedure, often referred to as a radio-frequency ablation (RFA), sends radioactive heat or ultrasound through a catheter to the hyperactive nerves, disrupting the signals around the renal arteries. This can lower blood pressure in patients suffering from resistant hypertension.
Who May Benefit From Renal Artery Denervation?
You may be a candidate for RND if you have tried various high blood pressure medications but continue to have resistant hypertension. Others who have side effects or have trouble remembering to take their medication may also benefit from RND.
Lowering your blood pressure is essential for reducing the risk of stroke, heart attack, and other forms of cardiovascular disease. Seeing a vascular specialist in Singapore to assess your blood pressure issues and overall health is important for moving forward with proper treatment.
How the Procedure Works – Step-By-Step Overview
If you are experiencing resistant hypertension in Singapore, set up an initial consultation and evaluation with Dr. Manish Taneja to review your health history and assess your high blood pressure risk factors. You will receive blood testing and imaging to evaluate your heart and kidney health.
If you are a candidate for renal artery denervation, we will schedule an appointment for this minimally invasive procedure. It will entail:
- A small puncture in the groin or wrist
- The catheter will be navigated into your renal arteries
- Controlled energy will be delivered to disrupt the sympathetic nerves
The procedure typically takes 45-60 minutes. You may be released later that day or have a short hospital stay, depending upon your response to the procedure and overall health.
Safety, Effectiveness & Current Evidence
Because RDN is a targeted, minimally invasive approach, there have been low rates of complications from the procedure. It is important to note that RDN is not a cure for high blood pressure but supports long-term control.
What to Expect After Renal Artery Denervation
Typically, RDN patients are up and walking within hours of the procedure and can return to their normal activities quickly. Routine blood pressurempor monitoring should be done, with gradual positive improvements seen in the following weeks and months.
It is important for patients to be seen at the Supreme Vascular and Interventional Clinic on a regular basis to check for medication adjustments following the RDN procedure. Lifestyle habits are still highly important including proper diet and exercise, as well as low-salt intake.
When to Consider a Specialist Assessment
High blood pressure that remains difficult to control may require a more detailed evaluation to understand the underlying causes and explore additional treatment options.
Consider seeking a specialist assessment if you:
- Have high blood pressure that remains uncontrolled despite taking prescribed medications
- Require multiple blood pressure medications but your readings remain above target
- Have been diagnosed with resistant hypertension
- Have concerns about the long-term impact of uncontrolled blood pressure on your heart, kidneys or blood vessels
- Would like to understand whether minimally invasive treatments such as renal artery denervation may be appropriate
- Would like a second opinion regarding your hypertension management plan
A specialist consultation includes reviewing your blood pressure history, medications, kidney function, cardiovascular risk factors and relevant imaging to determine the most appropriate treatment approach.
Seek urgent medical attention if you experience symptoms associated with dangerously high blood pressure, such as chest pain, severe shortness of breath, sudden weakness, difficulty speaking, severe headache or sudden vision changes.
Exploring Advanced Options for Better Blood Pressure Control
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Keep Varicose Veins and Spider Veins at Bay
If your legs feel sore persistently, achy when standing long periods, or maybe you notice blue or purple veins even bulging in the area, chances are these symptoms of varicose veins and spider veins could lead to other serious venous diseases such as Deep Vein Thrombosis (DVT), Chronic Venous Insufficiency (CVI), or Leg Swelling due to increased pressure forming larger blood clots over time. Varicose veins are fully treatable with minimally invasive procedures and treatments offering minimal downtime and quick recovery preventing further complications. Long term effects of untreated varicose veins can hinder your daily life and impact your health.
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