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Woman after a thyroid ultrasound

Hypothyroidism is a common thyroid disorder that results from malfunctioning of the gland involving a variety of symptoms and factors. It happens when the thyroid doesn't produce enough hormones and is also called an underactive thyroid. A thyroid specialist provides an individualized treatment plan based on the severity of the condition and the patient's specific needs.

Dr. Manish Taneja
Thyroid Nodule Specialist, Supreme Vascular and Interventional Clinic

Introduction to Hypothyroidism (Underactive Thyroid)

 

The thyroid is a butterfly-shaped gland in the neck, which produces thyroxine and triiodothyronine hormones. The thyroid gland plays a crucial role in regulating various functions in the human body, which is why it is so important for overall health and the proper functioning of organs.

This small but mighty gland is responsible for producing the hormones triiodothyronine (T3) and thyroxine (T4). These hormones are released into the bloodstream and regulate various body functions, including metabolism, internal temperature, breathing, weight, hair and nail growth, and brain development.

Hypothyroidism is a common thyroid disorder that results from malfunctioning of the gland. Other thyroid disorders include hyperthyroidism, thyroiditis, thyroid nodules, goiter, and thyroid cancer.  

If you or a loved one is experiencing thyroid issues, continue reading to learn about hypothyroidism symptoms, causes, diagnosis, and treatment.

Common Questions About Hypothyroidism

What is hypothyroidism?

Hypothyroidism, also known as an underactive thyroid, occurs when the thyroid gland does not produce enough thyroid hormones to meet the body's needs.

Thyroid hormones help regulate many important body functions, including:

  • Metabolism
  • Heart rate
  • Body temperature
  • Energy production
  • Digestion

When hormone levels are too low, these processes slow down, leading to a range of symptoms that often develop gradually.

What are the common symptoms of hypothyroidism?

Symptoms vary from person to person and may develop slowly over time.

Common symptoms include:

  • Persistent tiredness or fatigue
  • Feeling unusually cold
  • Unexplained weight gain
  • Dry skin
  • Constipation
  • Slower heart rate
  • Depression or low mood
  • Memory or concentration difficulties
  • Hoarse voice
  • Puffy face
  • Muscle weakness or aches

Many of these symptoms can also occur with other medical conditions, so proper assessment is important before making a diagnosis.

What causes hypothyroidism?

Hypothyroidism can develop for several reasons.

Common causes include:

  • Autoimmune thyroid disease, such as Hashimoto's thyroiditis
  • Previous thyroid surgery
  • Radioactive iodine treatment
  • Certain medications
  • Congenital thyroid disorders
  • Iodine deficiency, although this is uncommon in Singapore

Occasionally, thyroid nodules or other thyroid conditions may coexist with hypothyroidism, requiring further assessment.

How is hypothyroidism diagnosed?

Diagnosis usually involves a combination of clinical assessment and blood tests.

Your doctor may recommend:

Thyroid function blood tests

These commonly include:

  • Thyroid-stimulating hormone (TSH)
  • Free thyroxine (Free T4)

Thyroid ultrasound

An ultrasound may be recommended if:

  • A thyroid lump is present
  • The thyroid gland feels enlarged
  • Thyroid nodules are suspected

Imaging helps assess the structure of the thyroid but does not replace blood tests for evaluating thyroid function.

How is hypothyroidism treated?

Treatment aims to restore normal thyroid hormone levels.

For many patients, treatment involves daily thyroid hormone replacement medication prescribed by a doctor.

Regular follow-up helps ensure:

  • Appropriate hormone levels
  • Improvement in symptoms
  • Adjustment of medication when necessary

Treatment plans are individualised according to blood test results, symptoms and overall health.

What is Hypothyroidism?

 

Hypothyroidism, also known as underactive thyroid, is a condition whereby the thyroid fails to produce enough thyroid hormones (triiodothyronine (T3) and thyroxine (T4)). The body requires an adequate supply of these hormones to function optimally, without which many key functions are slowed down.

Patients with hypothyroidism may experience slowed metabolism, weight gain, breathing problems, temperature control issues, muscle weakness, and interrupted brain functioning, among other problems.

 

Who is Predisposed to Hypothyroidism?

Hypothyroidism affects 5-10% of the population. According to studies, the condition affects around 5% of the population, while another 5% is undiagnosed.

Anyone can develop hypothyroidism, including infants, but older people (60+) are more predisposed. Women are also more likely to be affected compared to men. Other factors that increase the risk include:

  • Past thyroid treatment, such as surgery
  • Previous thyroid disorders like goiter
  • Family history of thyroid disease
  • Thyroid, neck, or chest radiation treatment
  • Recent pregnancy

People with the following conditions may also have an increased risk of developing hypothyroidism:

  • Turner syndrome
  • Celiac disease
  • Diabetes
  • Rheumatoid arthritis
  • Lupus
  • Pernicious anemia
  • Sjogren syndrome

Symptoms of Hypothyroidism

Subclinical (mild) hypothyroidism may be asymptomatic. However, moderate to severe underactive thyroid presents symptoms that require management. While extremely low levels of thyroid hormones can be life-threatening, potentially leading to heart failure or coma, the condition is well manageable with proper treatment.

Common symptoms of hypothyroidism include:

  • Inability to tolerate cold
  • Gaining weight
  • Fatigue
  • Constipation
  • Muscle soreness or pain
  • Slowed heart rate
  • Decreased sweating
  • Depression
  • Brain fog
  • Heavy and irregular menstrual cycle
  • Dry skin and hair
  • Hoarse voice

Hypothyroidism may also lead to complications such as high cholesterol, myxedema coma, mental issues, goiter, heart problems, and hearing loss.

    Causes of Hypothyroidism

     

    There are several causes of hypothyroidism, including:

    • Hashimoto's disease (antibodies attack the thyroid gland)
    • Thyroiditis (inflammation of the thyroid)
    • Radiation treatment during the treatment of hyperthyroidism may destroy thyroid cells
    • Congenital hypothyroidism (occurs when a baby is born with an underdeveloped thyroid)
    • Some medicines (e.g., heart and cancer medicines)
    • Part or complete removal of the thyroid during treatment of a thyroid problem

     

    Diagnosis of Hypothyroidism

     

    The presence of hypothyroidism symptoms does not necessarily mean you have the condition. A doctor may need to conduct a physical exam, evaluate your medical history, and perform tests. If you're experiencing any of the symptoms list above, It's important to seek guidance from a thyroid nodule specialist in Singapore.

    Common tests for diagnosing hypothyroidism include blood and imaging tests.

     

    Hypothyroidism Treatment and Management

    Maybe you're wondering – can hypothyroidism be cured?

    Unfortunately, there's no cure for hypothyroidism currently. But there's an appropriate treatment to manage the condition and enable you to lead a quality life. Typical treatment involves hormonal replacement using levothyroxine and thyroxine replacement pills. These are thyroid hormone medicine administered orally and will be able to bring back your hormones to normal levels. Your doctor will also monitor your hormone levels periodically after using the hypothyroidism medication. If you encounter any symptoms, it's best to raise them as well.

    High-iodine foods, such as eggs, iodized salt, and dairy products, may benefit some patients since iodine is essential for thyroid hormone production. However, patients with autoimmune thyroid disorders may be intolerant of iodine. In such a case, your doctor may recommend you avoid certain foods likely to worsen symptoms.

    Hypothyroidism Prevention

    Sadly, hypothyroidism is not preventable. However, proper management can enable you to lead a healthy, normal life.

    While there's no cure for hypothyroidism yet, with proper treatment, there are ways you can manage the condition and lead a quality life. In addition, timely treatment is vital to avoid serious complications.

    The endocrine system plays a crucial role in coordinating and controlling many functions in the body, including metabolism, growth and development, mood, and immune responses. If left untreated, it can lead to various health issues. Diagnosis and management of these thyroid conditions such as hypothryoidism often involve hormone replacement therapy, lifestyle modifications, and close medical monitoring.

    When to Consider a Thyroid Specialist Assessment in Singapore

    Symptoms of hypothyroidism often develop gradually and can overlap with many other health conditions. A specialist assessment helps determine whether your symptoms are related to thyroid disease and whether additional investigation is needed.

    Consider arranging a specialist assessment if you:

    • Have persistent fatigue, weight changes or cold intolerance.
    • Have abnormal thyroid function blood tests.
    • Notice a lump or swelling in your neck.
    • Have been diagnosed with thyroid nodules.
    • Experience difficulty swallowing or pressure in the neck.
    • Have a family history of thyroid disease.
    • Want a second opinion regarding your thyroid diagnosis or treatment plan.
    • Wish to understand whether monitoring, minimally invasive treatment or surgery is appropriate for a coexisting thyroid nodule.

    At the Supreme Vascular and Interventional Clinic, assessment focuses on understanding both thyroid function and thyroid structure. When thyroid nodules are present, your specialist can review ultrasound findings, discuss whether additional investigations are required, and explain personalised management options, including monitoring and minimally invasive treatments where appropriate.

    Thyroid Nodules

    The Supreme Vascular and Interventional Clinic understands the concern and uncertainty surrounding thyroid nodules. If you’ve discovered a lump in your neck, we’re here to provide clarity, comprehensive care, and thyroid nodule treatments.

    Other Health Conditions

    The Supreme Vascular and Interventional Clinic is your "go-to" facility for various conditions and pain management. To arrange an appointment with Dr. Manish Taneja, our thyroid nodules specialist in Singapore, contact us. You can also call us at (+65) 6904 8084 for a consultation.